
Biostate’s Solution for RNAseq
Gene Expression Data – Simplified, Accelerated, Affordable
Obtaining accurate gene expression data from RNAseq workflows is both costly and complex. Traditional depletion or enrichment steps used to target RNAs of interest rely on expensive enzymes, introduce a variety of biases, or exclude lncRNAs (long noncoding RNAs).
To address these challenges, Biostate has developed an innovative solution that integrates two proprietary technologies:
BIRT (Barcode-Integrated Reverse Transcription) – for efficient sample multiplexing PERD (Probes for Excess RNA Depletion) – for nonenzymatic depletion of ribosomal RNA (rRNA) Together, BIRT+PERD delivers key advantages:
1. 16x increase in sample throughput
2. Up to 90% reduction in cost
3. Ability to measure lncRNAs
4. Compatibility with low-yield, degraded samples or budget-constrained projects
By adopting BIRT+PERD, NGS service providers can expand their client base, increase operational efficiency, and deliver superior value across research, clinical, and pharmaceutical sectors.